© Benaki Phytopathological Institute
Kasiotis & Machera
44
go, J.L. 2008b. Human dietary exposure to
hexachlorobenzene in Catalonia, Spain.
Journal
of Food Protection,
71: 2148-2152.
Marti-Cid, R., Llobet, J.M., Castell, V. and Domingo,
J.L. 2008c. Human exposure to polychlorinat-
ed naphthalenes and polychlorinated diphe-
nyl ethers from foods in Catalonia, Spain: tem-
poral trend.
Environmental Science & Technology,
42: 4195-4201.
Matsuda, K., Shimomura, M., Ihara, M., Akamatsu, M.
and Sattelle, D.B. 2005. Neonicotinoids show se-
lective and diverse actions on their nicotinic re-
ceptor targets: electrophysiology, molecular bi-
ology, and receptor modeling studies.
Bioscience,
Biotechnology, and Biochemistry,
69: 1442-1452.
Mohamed, F., Gawarammana, I., Robertson, T.A.,
Roberts, M.S., Palangasinghe, C., Zawahir, S.,
Jayamanne, S., Kandasamy, J., Eddleston, M.,
Buckley, N.A., Dawson, A.H. and Roberts, D.M.
2009. Acute human self-poisoning with imida-
cloprid compound: a neonicotinoid insecticide.
PloS one,
4: e5127.
Nauen, R., Ebbinghaus-Kintscher, U. and Schmuck,
R. 2001. Toxicity and nicotinic acetylcholine re-
ceptor interaction of imidacloprid and its me-
tabolites in Apis mellifera (
Hymenoptera: Api-
dae
).
Pest Management Science,
57: 577-586.
Nomura, H., Ueyama, J., Kondo, T., Saito, I., Mura-
ta, K., Iwata, T., Wakusawa, S. and Kamijima, M.
2013. Quantitation of neonicotinoid metabo-
lites in human urine using GC-MS.
Journal of
Chromatography, B
941: 109-115.
Parron, T., Hernandez, A.F. and Villanueva, E. 1996.
Increased risk of suicide with exposure to pes-
ticides in an intensive agricultural area. A 12-
year retrospective study.
Forensic Science Inter-
national,
79: 53-63.
Pollack, P. 2011.
Fine chemicals: the industry and the
business
, 2nd edition ed. John Wiley & Sons,
New Jersey.
Proenca, P., Teixeira, H., Castanheira, F., Pinheiro, J.,
Monsanto, P.V., Marques, E.P. and Vieira, D.N.
2005. Two fatal intoxication cases with imida-
cloprid: LC/MS analysis.
Forensic Science Interna-
tional,
153: 75-80.
Ramanathan, R., Jemal, M., Ramagiri, S., Xia, Y.Q.,
Humpreys, W.G., Olah, T., Korfmacher, W.A.,
2011. It is time for a paradigm shift in drug dis-
covery bioanalysis: from SRM to HRMS.
Journal
of Mass Spectrometry,
46: 595-601.
Simon-Delso, N., Amaral-Rogers, V., Belzunces, L.P.,
Bonmatin, J.M., Chagnon, M., Downs, C., Furlan,
L., Gibbons, D.W., Giorio, C., Girolami, V., Goul-
son, D., Kreutzweiser, D.P., Krupke, C.H., Liess,
M., Long, E., McField, M., Mineau, P., Mitchell,
E.A., Morrissey, C.A., Noome, D.A., Pisa, L., Set-
tele, J., Stark, J.D., Tapparo, A., Van Dyck, H., Van
Praagh, J., Van der Sluijs, J.P., Whitehorn, P.R. and
Wiemers, M. 2015. Systemic insecticides (neoni-
cotinoids and fipronil): trends, uses, mode of ac-
tion and metabolites.
Environmental Science and
Pollution Research,
22: 5-34.
Taira, K. 2014. Human neonicotinoids exposure in Ja-
pan.
Japanese Journal of Clinical Ecology,
23: 14-
24.
Taira, K., Aoyama, Y., Kawakami, T., Kamata, M. and
Aoi, T. 2011. Detection of chrolopyridinyl neo-
nicotinoid insecticide metbolite 6-chloronico-
tinic aicd in the urine: Six cases with subacute
nicotinic symptoms.
Japan Journal of Clinical
Toxicology,
24: 222-230.
Taira, K., Fujioka, K. and Aoyama, Y. 2013. Qualitative
profiling and quantification of neonicotinoid
metabolites in human urine by liquid chroma-
tography coupled with mass spectrometry.
PloS
one,
8: e80332.
Togola, A., Baran, N. and Coureau, C. 2014. Advan-
tages of online SPE coupled with UPLC/MS/MS
for determining the fate of pesticides and phar-
maceutical compounds.
Analytical and Bioana-
lytical Chemistry,
406: 1181-1191.
Tomizawa, M., Maltby, D., Medzihradszky, K.F.,
Zhang, N., Durkin, K.A., Presley, J., Talley, T.T.,
Taylor, P., Burlingame, A.L. and Casida, J.E.
2007a. Defining nicotinic agonist binding sur-
faces through photoaffinity labeling.
Biochem-
istry,
46: 8798-8806.
Tomizawa, M., Talley, T.T., Maltby, D., Durkin, K.A.,
Medzihradszky, K.F., Burlingame, A.L., Taylor,
P. and Casida, J.E. 2007b. Mapping the elusive
neonicotinoid binding site.
Proceedings of the
National Academy of Sciences of the United States
of America,
104: 9075-9080.
Ueyama, J., Nomura, H., Kondo, T., Saito, I., Ito, Y.,
Osaka, A. and Kamijima, M. 2014. Biological
monitoring method for urinary neonicotinoid
insecticides using LC-MS/MS and its applica-
tion to Japanese adults.
Journal of Occupation-
al Health,
56: 461-468.
Uroz, F.J., Arrebola, F.J., Egea-Gonzalez, F.J. and Mar-
tinez-Vidal, J.L. 2001. Monitoring of 6-chloronic-
otinic acid in human urine by gas chromatogra-
phy-tandem mass spectrometry as indicator of
exposure to the pesticide imidacloprid.
Analyst,
126: 1355-1358.
Van Eeckhaut, A., Lanckmans, K., Sarre, S., Smolders, I.
and Michotte, Y. 2009. Validation of bioanalytical
LC-MS/MS assays: evaluation of matrix effects.
Journal of Chromatography B,
877: 2198-2207.
Vanengelsdorp, D., Evans, J.D., Saegerman, C., Mull-
in, C., Haubruge, E., Nguyen, B.K., Frazier, M., Fra-
zier, J., Cox-Foster, D., Chen, Y., Underwood, R.,
Tarpy, D.R. and Pettis, J.S. 2009. Colony collapse
disorder: a descriptive study.
PloS one,
4: e6481.
Wu, I.W., Lin, J.L., Cheng, E.T., 2001. Acute poisoning
with the neonicotinoid insecticide imidacloprid
in N-methyl pyrrolidone.
Clinical Toxicology,
39:
617-621.
