Page 20 - Volume 3, Issue 2, July 2010

© Benaki Phytopathological Institute
Mihou & Michaelakis 50
Zn(BH4)2 reduction of the produced ketone
to the diol 97. More functional and protec-
tive group manipulations led to the inter-
mediate 69a which could be transformed to
the desired pheromone according to litera-
ture (Machiya et al., 1985).
2.8.Oxidative cyclization with Ru(+2)
complexes
The synthetic utility of the oxidative cy-
clization of bis-homopropargylic alcohols
with Ru(+2) complexes as catalysts and N-hy-
droxysuccinimide to form δ-lactones was il-
Figure 29
Figure 30
Figure 31